Disease and POPs

Persistent Organic Pollutants (POPs) are responsible for a wide range of metabolic diseases that clinicians in Establishment Medicine know nothing about. Even if they understood the problems POPs cause, they have no methods by which they could eliminate the threat.

I want to concentrate on some of the big diseases:

  • Obesity
  • Diabetes
  • Cardiovascular Disease
  • Cancer including Breast Cancer

The chemicals contributing to obesity are known as obesogens. Here’s something I just dug up at http://xfinity.net/blogs/lifestyle/2013/10/14/animals-are-having-an-obesity-crisis/too/

Americans aren’t the only ones getting fatter—our animals are also growing overweight, reports it isn’t just pets and lab animals piling on the pounds (though they are; the likelihood of chimps living with or near humans being obese increased tenfold between 1985 and 2005): one study found feral rats in Baltimore are also getting plumper. This is more than just an interesting piece of trivia, Pro Publica reports:

The following idea will shock people who believe we found the solution to the obesity epidemic. It raises the question of whether the usual culprits of “too much food” and “not enough exercise” are really the only things causing the obesity crisis.

And the evidence is overwhelming that it is more, much more.

Breast Cancer

Persistent organic pollutants (POPs) are a class of synthetic, lipophilic, bioaccumulative compounds, many of which were first introduced during the post WWII industrial boom. Most notable among these older POPs are dichlorodiphenyl trichloroethane (DDT) and polychlorinated biphenyls (PCBs), which were banned in the 1970s in the U.S. due to concerns over widespread human exposures and potential adverse health effects in wildlife and humans.

Because of their persistent and bioaccumulative nature, however, exposure to these compounds continues decades later with detectable levels prevalent in human tissue today. Polybrominated diphenyl ethers (PBDEs) are a newer class of POPs, introduced into the marketplace in the late 1970s as flame retardant additives to consumer and building products.   Owing to their similar molecular structure and toxicological properties to PCBs, in combination with the ubiquity of exposure, it appears PBDEs are poised to become the PCBs of the 21st century. In response to recent regulatory action that banned the use of two of the three primary commercial PBDE formulations in the U.S., replacement brominated flame retardants (BFRs) have recently emerged and are in widespread use. 

Interest in the role of POPs in breast cancer etiology stems largely from the well-documented endocrine disrupting properties of these compounds.

 

 

 

Inflammation as a Leading Cause of Chronic Disease

Chronic inflammation is now thought to play a key pathogenetic role in the associations of obesity with insulin resistance and diabetes.

Data from the National Health and Nutrition Examination Survey (NHANES) 1999-2002 revealed strong associations of serum concentrations of persistent organic pollutants (POPs) with type 2 diabetes.  It is well-known that exposure to high concentrations of environmental pollutants can induce inflammation.

In this study, we observed that serum concentrations of OC pesticides were positively associated with C-Reactive Protein among the general population of the U.S. with background exposure to POPs.

There is no question that the exposure to certain environmental pollutants can induce inflammation. At present, the most studied area in both experimental and human studies subsumes the association between exposure to air pollution and system inflammation.

As an entirely nonspecific response to most forms of tissue damage, various factors may be involved in the chronic elevation of CRP. Our study suggested that, without consideration of exposure to POPs, CRP may not be associated with insulin resistance.

The Incidence of Obesity and Diabetes has Dramatically Increased Worldwide

From 1980 to 2008, the global prevalence of obesity has doubled in both men and women whereas the number of people with diabetes increased from 153 million in 1980 to 347 million in 2008. A recent report realized in the European Union (EU) highlights that overweight and obesity affect more than 50% of the adult population whereas diabetes is now affecting over 30 million people. In the United States (US), the prevalence of obesity among children and adolescents has almost tripled since 1980, and 12% of children aged 2 through 5 years were obese in 2009-2010. In addition to enhancing the risk of premature death, diabetes and obesity are major causes of multiple complications, including hypertension, cardiovascular diseases, asthma, blindness, limb amputation, and sleep apnea, that generate enormous economic costs for both health care and loss of productivity to society. Total annual economic cost of diabetes in the US reached $132 billion in 2002, representing around 11% of the US health care expenditure, and increased to $174 billion in 2007. In Europe, obesity-related healthcare was estimated to reach up to 10.4 billion Euros.

Although they are the focus of intense investigations, the origins of metabolic diseases have remained poorly understood.

Persistent organic pollutants (POPs), including dioxins, furans, polychlorinated biphenyls (PCBs), and organochlorine pesticides, are chemicals mainly created by industrial activities, either intentionally or as by-products. Because of their ability to resist environmental degradation, these substances are omnipresent in food products, and found all around the world, even in areas where they have never been used like Antarctica . Thus, virtually all humans are daily exposed to POPs. In the general population, exposure to POPs comes primarily from the consumption of animal fat like fatty fish, meat and milk products; the highest POP concentrations being commonly found in fatty fish.

Environmental toxins; POPs

The most important cause of type 2 diabetes and the metabolic syndrome is environmental. Something bad was introduced during industrialization and is increasing in the environment. We know that it is noninfectious; the usual suspects are “POPs.” POPs are defined as “chemical substances that persist in the environment, bio-accumulate through the food web, and pose a risk of causing adverse effects to human health and the environment” by the Stockholm Convention. It identified 12 POPs initially and subsequently added 9 more.

Scientific Evidence for the Homeopathic Treatment of Environmental Poisons

There is a significant body of research to show the benefits of homeopathic medicines in treating environmental exposures of toxic substances.

Back in 1994, a highly respected group of researchers reviewed 105 animal studies that evaluated the ability of homeopathic medicines to discharge heavy metals from the bodies of mice. This review found that the best results were in the studies that were deemed to be scientifically rigorous. When evaluating only these higher quality studies, the researchers found a significant reduced death rate from exposure to toxic minerals (arsenic, mercury, cadmium, bismuth) when homeopathic doses of these substances were given to the animals (as compared with those given a placebo).

Since 1994, more than a dozen new studies have confirmed these results. A group of university researchers in India have conducted a body of laboratory trials testing the effects of heavy metals on mice which were given homeopathic doses of these toxic substances after exposure.

At present, arsenic in groundwater has affected millions of people globally distributed over 20 countries. In parts of West Bengal (India) and Bangladesh alone, over 100 million people are at risk, and supply of arsenic-free water is grossly inadequate.

Attempts to remove groundwater arsenic by using orthodox medicines have mostly been unsuccessful. A potentized homeopathic remedy made from arsenic (Arsenicum album 30C) was administered in a double-blind, placebo-control study to a group of groundwater arsenic affected people, and the arsenic contents in urine and blood were periodically evaluated. The activities of various toxicity marker enzymes and compounds in the blood, namely aspartate amino transferase, alanine amino transferase, acid phosphatase, alkaline phosphatase, lipid peroxidation and reduced glutathione, were also periodically monitored up to three months. The results are highly encouraging and suggest that the drug can alleviate arsenic poisoning in humans.

Based on this research, it is reasonable to ask if homeopathic doses of radioactive elements and other substances with apparently similar effects are useful.

 

The Solution to Pollution is Dilution – Part 3 of 7

http://www.leclinic.com – In this video we discuss the third phase of homotoxicology, the deposition phase. We tell you how you can measure the impact of pha…

 

Seeing the Direct Effects of Using Homeopathic Remedies to Fight Diabetes

Now that we know that POPs are a primary cause of diabetes it just makes sense to use a proven method to help the body eliminate these disease-causing toxins. This is exactly what we do in our clinical practices.

 

Environmental Chemicals Cause Weight Gain

There’s no question that diet composition has effects that optimize changes in bodyweight and particularly in body composition. A low-carbohydrate diet helps one reduce food intake, leading to a body composition that has more muscle and less fat.

The “super-market diet,” in contrast, increases over-all calorie intake and makes bodyweight control more difficult.

Glycemic Index

Many decades ago, several researchers implicated insulin, produced by the pancreas in response to the consumption of carbohydrates, as a cause of major health problems.

During the 1990’s, there was an explosion of interest among scientists, medical practitioners, and lay people about the potential hazards of carbohydrate consumption and its associated glucose and insulin releases.

All of this occurred simultaneously with a national celebration of the health-giving properties of these same glucose and insulin-raising carbohydrates.

Fat had already been dissed for decades, and now carbohydrates, also, too, were falling into disfavor. The problems were mounting.

If carbohydrates were bad, along with fats, what were people going to eat? To solve this problem, researchers were doing some neat arm-twisting.

Several researchers and popular authors are unconvinced about the hazards of a high-fat diet. They, in contrast to the fat-fearing majority, have proposed the reduction of carbohydrates to the point that they represent a small percentage of total daily calorie intake.

Most scientists and pseudo-scientific writers are fearful of going against the “Establishment” theory that fat is the cause of many major diseases.

This group, however, has been subject to the influence of 25 years of study into the “Glycemic Index.”

Another dietary choice for people, other than the low-carbohydrate diet, is that of the glycemic index. Here, one chooses carbohydrate foods that don’t lead, theoretically, to a rapid or prolonged increase in blood sugar (glucose) and insulin.

But that’s the rub: there’s no convincing scientific evidence supporting the usefulness of the glycemic index!

As of 2002, no international or national organization has accepted the tenets of the Glycemic Index to assist diabetic patients in maintaining control for blood sugar levels.

Recent Research Shows that Unexpected Culprits are Confounding the Problem

Chemicals as heavy metals, some solvents, pesticides, BPA, organophosphates, phthalates, PCB, PBBs, and many other substances are documented to cause weight gain. These chemicals interfere with weight and fat balance by various mechanisms related to weight-controlling hormones, activity of the sympathetic nervous system, and sensitivity to neurotransmitters.

Exposure to these chemicals varies in different age groups; their effects during fetal and infancy periods may be irreversible and long-lasting for adulthood. Even exposure to low doses of endocrine disrupting chemicals during critical times of differentiation can change the developmental programming and may result in obesity. One hypothesis on the effects of intrauterine growth on fetal programming and fetal origins of adult diseases is well documented; however, other characteristics as later growth spurt and environmental factors are considered to influence this programming. Exposure to environmental chemicals with endocrine-disrupting activities in early life may result in everlasting adverse health effects. Such health consequences may become apparent not only in childhood, but also in adulthood, and even in succeeding generations. Transgenerational effects may be because of mutations as well as because of factors regulating gene expression. Findings support the role of obesogens, as chemicals with disruptive effects on fat balance and various weight controlling mechanisms, in programming the development of excess weight from early life. Although all obesogen chemicals are not yet identified, and their detailed mechanisms of action remain to be explored, generally it is assumed that exposure to different doses of these environmental chemicals in various periods of life from fetal to adult period interacts with some endocrine signaling mechanisms and in turn leads to obesity.

It’s no longer simple!